Adrenal Disorders of Pregnancy

15 08 2008

There are probably many women out there who have adrenal fatigue and pregnancy, though they may not know they have adrenal problems. I know I have adrenal fatigue as well as being pregnant, just into my third trimester. I have felt better since being pregnant, but adrenal fatigue is still a daily struggle to deal with. For those of you women who have adrenal fatigue and have recently become pregnant or are well into their pregnancy, I hope this following section offers some insight. If need adrenal fatigue support, I recommend visiting the Adrenal Fatigue Yahoo support group at:


Chapter 2B – Peter R Garner, MD


During pregnancy increased steroid hormone production is essential to meet both the maternal demand for increased estrogens and cortisol and the fetal demand for reproductive and somatic growth and development. In addition, alterations in the renin-angiotensin-aldosterone cascade are required to allow for a 50% increase in maternal blood volume without resulting in hypertension. These changes occur through a complex interaction amongst maternal and fetal endocrine systems in the placenta.


The normal adult adrenal gland weighs approximately 5gms and during pregnancy increases only slightly in size. Histologically, the zona fasciculate (glucocorticoids) widens during pregnancy, which is suggestive of increased secretion. The zona glomerulosa (mineralo-corticoids) and zona reticularis (androgens) remain unchanged in width (1,2).


To read the rest of this section, please visit:




2 responses

1 09 2008

Thanks for posting on this — I think that AF and pregnancy is a really overlooked topic and probably one that affects lots of women (me included). I’ve found this article about how to eat for adrenal health to be pretty good: — and one that is easily adaptable to a prenatal diet.

– Jacqueline
co-author, Big, Beautiful, and Pregnant

9 06 2011
Orgainc Kukuru

I read your all content. You did very good job. I know that large quantities of estrogen are produced during normal human pregnancy, and, after the first 3-4 weeks of gestation, the placenta produces nearly all of the estrogen. And only a small amount of the steroids in the maternal circulation reach the fetal compartment in normal pregnancy. This experiences I shared you from my life.

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